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KMID : 0361720120230040273
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Korean Journal of perinatology
2012 Volume.23 No. 4 p.273 ~ p.279
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Two Cases of Congenital Cytomegalovirus Infection with Pulmonary Hypertension
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Kim Ah-Young
Kim Yong-Seok
Park Kyung-Hee
Byun Shin-Yun
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Abstract
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Cytomegalovirus (CMV) is the most common cause of intrauterine infection. 90% of congenital CMV infection being asymptomatic, only 5% of CMV infections are presented with severe symptoms: intrauterine growth retardation, petechia, hepatosplenomegaly, thrombocytopenia, hearing loss and mental retardation. We experienced two cases of symptomatic congenital CMV infection with persistent pulmonary hypertension in NICU who presented intrauterine growth retardation, petechia, cholestasis, hepatosplenomegaly, and thrombocytopenia. Persistent pulmonary hypertension improved after ventilator care, and hearing loss also improved after ganciclovir treatment for 6 weeks.
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KEYWORD
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Cytomegalovirus, Pulmonary hypertension
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